The prostate is a common site of disease in patients with MEN2B and MTC

A recent study looked at young men with MEN2B (also known as MEN3), which causes medullary thyroid cancer. Doctors found that problems in the prostate were more common than previously thought, even in teenagers. In some cases, small growths in the prostate looked very similar to the thyroid cancer itself, and sometimes appeared before the cancer had spread anywhere else. These findings suggest that the prostate may be an important but overlooked site of disease in MEN2B. The research shows that checking the prostate in teenage and adult males with MEN2B may help doctors spot changes earlier, especially if blood test results rise unexpectedly or urinary symptoms appear.

Ref: Kraft, I. L., Akshintala, S., Gross, A., Dombi, E., Turkbey, B., Bednarova, S., Ward, J. F., Yedururi, S., Merino, M., Pinto, P. A., Widemann, B. C., Shern, J. F., Waguespack, S. G., & Glod, J. (2026). The prostate is a common site of disease in patients with MEN2B and medullary thyroid carcinoma. Endocrine-Related Cancer, 33(1), Article e240243, e240243. Retrieved Feb 4, 2026, from https://doi.org/10.1530/ERC-24-0243
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