Familial Isolated Pituitary Adenoma (FIPA)
Last Updated on Monday, 18 February 2013 10:29 Written by Jo Grey Thursday, 26 January 2012 16:00
The pituitary gland sits near the base of the brain behind the nose in a bony box called the sella turcica, and is roughly the size and shape of a bean. It is part of the body’s endocrine system, which is made up of a number of glands that release hormones (the body’s chemical messengers) into the bloodstream. Pituitary hormones are important for growth and development, metabolism (turning food into energy) and reproduction.
What is Familial Isolated
A pituitary adenoma is a slow-growing and benign (non-cancerous) tumour of the pituitary gland which occurs in about 1 person in every 1000. Only 5% (1 in 20) of these tumours are hereditary, meaning that they are passed down through families. Familial Isolated Pituitary Adenoma (FIPA) is one of a small number of rare genetic disorders that can cause hereditary pituitary tumours.
Patients diagnosed with FIPA are said to have ‘isolated’ pituitary adenomas because, unlike in some other hereditary endocrine disorders, they do not have an increased risk of developing tumours in any other glands in the body.
Some pituitary gland tumours may produce abnormally increased amounts of hormones which in turn can cause a variety of symptoms.
For further detailed information on Familial Isolated Pituitary Adenoma (FIPA), please read the AMEND patient information booklet which was produced in August 2012 with the assistance of the AMEND Medical Advisory Team and Professor Marta Korbonits from St Bartholomew's Hospital in London.
FIPA Patient Information Book (870.43 kB). We recommend that you discuss the content of this booklet with your specialist - it is not for use in self-diagnosis, and not all of the information it contains may be relevant to you.
Author: Jo Grey, AMEND CEO, with the help of the AMEND Medical Advisory Team