It is possible in some families to have a genetic test to see whether someone has inherited the gene fault. However, the first step is to have a blood sample tested from someone with MEN in the family. With this initial test (mutation screen), the result may not be received for a number of months, and, indeed, the gene fault is not always found. If the gene fault is found, a blood test (predictive genetic testing) may then be offered to other members of the family. The results from predictive genetic testing are received normally within several weeks. There are a number of issues surrounding predictive genetic testing particularly in relation to children and as such, all patients should be seen and counselled by a consultant clinical geneticist. If the gene fault cannot be found or if a blood sample from an affected person cannot be obtained then predictive genetic testing cannot be done.

Having children tested is a very individual decision, however , if children of a known MEN parent are tested, those unaffected can rest assured that no further investigations are required. Those who have inherited the gene can be comforted by the fact that testing and treatment patterns will determine as early as possible when intervention is required. Thanks to this early detection by DNA test, complications from the conditions associated with the MEN syndromes , may be drastically reduced.

Genetic testing and counselling is available at 23 regional genetic centres throughout the UK ( www.bshg.org.uk ). A referral to a genetic centre is usually made through your GP or specialist.