The body’s two adrenal glands are normally each about the size of a whole walnut and sit just on top of the kidneys. A growth of the inner part of the adrenal gland is called a phaeochromocytoma (fee-o-cromo-sy-toma) and is almost always benign (not cancerous) in MEN. Phaeochromocytomas may grow for many years without causing severe symptoms but can be activated by events such as childbirth or surgery. Symptoms are varied and may include all or some of the following: sudden migraine-like headaches, palpitations, breathlessness, excessive sweating, high (or rarely low) blood pressure (constant or off- and-on), trembling, tiredness, depression, anxiety, and nausea with or without vomiting. These growths may be detected using blood and urine tests as well as several different types of scan. Treatment involves an operation to remove the gland and growth. A period of medication before surgery is necessary to control the unstable blood pressure. If both adrenal glands are removed, lifelong medication is necessary.